Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSH | P09668 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380828 | 0.87 | GPR35 (0.50) | MAPTALDH1A1HPGDABCC1ABCG2 | |
| SCHEMBL11266563 | 0.84 | MAPT (0.49) | MAPTALDH1A1MAPK1HPGDABCC1 | |
| SCHEMBL9306308 | 0.84 | MAPT (0.62) | MAPTALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL29484215 | 0.84 | MAPT (0.67) | MAPTALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL4368126 | 0.84 | MAPT (0.67) | MAPTALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL15266199 | 0.78 | ABCG2 (0.54) | MAPTALDH1A1MAPK1HPGDABCC1 | |
| SCHEMBL11220965 | 0.77 | MAPT (0.51) | MAPTALDH1A1MAPK1TSHRALOX15 | |
| SCHEMBL11277169 | 0.77 | MAPT (0.56) | MAPTALDH1A1ABCC1CYP2C19KMT2A | |
| SCHEMBL11263131 | 0.77 | QDPR (0.56) | MAPTALDH1A1MAPK1HPGDABCC1 | |
| SCHEMBL3559913 | 0.76 | CRHBP (0.68) | MAPTALDH1A1MAPK1HPGDABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366319-A | Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones | STERLING DRUG INC. (US) | 1982-12-28 | — | — | US | disclosed |
| US-4310531-A | 5-(Pyridinyl)-benzoxazol-2(3H)-ones and their use as cardiotonics | STERLING DRUG INC. (US) | 1982-01-12 | — | — | US | disclosed |