Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253421 | 0.94 | ALDH1A1 (0.37) | TSHRALDH1A1MAPK1LMNAHSD17B10 | |
| SCHEMBL11260937 | 0.89 | CYP19A1 (0.36) | TSHRALDH1A1MAPK1LMNAHSD17B10 | |
| SCHEMBL11260700 | 0.85 | CYP17A1 (0.35) | TSHRCYP19A1 | |
| SCHEMBL11252643 | 0.85 | TSHR (0.47) | TSHRALDH1A1MAPK1LMNAHSD17B10 | |
| SCHEMBL11253398 | 0.85 | ALDH1A1 (0.41) | TSHRALDH1A1MAPK1LMNAHSD17B10 | |
| SCHEMBL11255931 | 0.84 | TSHR (0.42) | TSHRALDH1A1MAPK1LMNAHSD17B10 | |
| SCHEMBL11270017 | 0.83 | QPCT (0.42) | ALDH1A1LMNAKDM4EPRKCICYP19A1 | |
| SCHEMBL11269138 | 0.83 | TSHR (0.42) | TSHRALDH1A1MAPK1LMNAHSD17B10 | |
| SCHEMBL10780799 | 0.82 | TBXAS1 (0.40) | HSD17B10PRKCI | |
| SCHEMBL11253152 | 0.81 | LMNA (0.44) | LMNAKDM4EPRKCICYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |