Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259539 | 0.82 | CYP2C19 (0.39) | CYP2C19TSHRLMNAMEN1KMT2A | |
| SCHEMBL28873103 | 0.75 | CYP2C19 (0.39) | CYP2C19TSHRLMNAKMT2A | |
| SCHEMBL11263469 | 0.72 | CYP2C9 (0.48) | LMNATDP1POLB | |
| SCHEMBL2191989 | 0.71 | ADAM17 (0.62) | CYP2C19TSHRLMNAADAM17 | |
| SCHEMBL3400918 | 0.71 | ADAM17 (0.62) | CYP2C19TSHRLMNAADAM17 | |
| SCHEMBL4123231 | 0.71 | ADAM17 (0.62) | CYP2C19TSHRLMNAADAM17 | |
| Mephenytoin SCHEMBL21768 | 0.69 | CYP2C19 (1.00) | CYP2C19TSHRLMNATDP1MEN1 | |
| Mephenytoin SCHEMBL21766 | 0.69 | CYP2C19 (1.00) | CYP2C19TSHRLMNATDP1MEN1 | |
| SCHEMBL27951965 | 0.68 | KMT2A (0.55) | CYP2C19TSHRLMNATDP1MEN1 | |
| SCHEMBL28873111 | 0.68 | CYP2C19 (0.35) | CYP2C19TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314023-A | AZO-METHINE DYES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |