SCHEMBL28873111

SCHEMBL28873111

CC(C)CC1(c2ccccc2)NC(=O)Oc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.35
TSHR P16473 1/20 0.35
ATM Q13315 2/20 0.33
GAA P10253 1/20 0.33
ADAM17 P78536 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ELANE P08246 1/20 0.32
LMNA P02545 1/20 0.32
CASP6 P55212 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11259539 0.82 CYP2C19 (0.39) CYP2C19TSHRATMADAM17MEN1
SCHEMBL28873103 0.82 CYP2C19 (0.39) CYP2C19TSHRKMT2ALMNASMN1; SMN2
SCHEMBL28873098 0.77 SLC6A1 (0.32) CYP2C19TSHRGAAMEN1KMT2A
SCHEMBL28873132 0.75 PRMT5 (0.33) CYP2C19TSHRGAAMEN1KMT2A
SCHEMBL28873100 0.74 P2RX7 (0.35) MEN1KMT2ALMNA
SCHEMBL10609425 0.72 ALDH1A1 (0.43) GAAMEN1KMT2ALMNA
SCHEMBL28873109 0.72 PRMT5 (0.40) CYP2C19GAAMEN1KMT2A
SCHEMBL20332078 0.71 ADAM17 (0.41) CYP2C19TSHRATMADAM17MEN1
SCHEMBL632647 0.69 PDK2 (0.37) CYP2C19GAAMEN1KMT2A
SCHEMBL20241797 0.69 ADAM17 (0.37) CYP2C19TSHRATMADAM17MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372625-B Method for preparing 4-alkyl methyl-4-aryl-1,3-benzoxazine-2 (4H) -ketone by blue light irradiation 常州大学 2022-11-01 CN disclosed