Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | SCN4A | P35499 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2191989 | 1.00 | ADAM17 (0.62) | ADAM17CYP2C19TSHRCACNA1FALDH1A1 | |
| SCHEMBL4123231 | 1.00 | ADAM17 (0.62) | ADAM17CYP2C19TSHRCACNA1FALDH1A1 | |
| SCHEMBL3655113 | 0.86 | ADAM17 (0.59) | ADAM17CACNA1FALDH1A1MAPTCYP2C9 | |
| SCHEMBL20135652 | 0.84 | ADAM17 (0.60) | ADAM17MMP2 | |
| SCHEMBL3410690 | 0.84 | ADAM17 (0.60) | ADAM17MMP2 | |
| SCHEMBL20135513 | 0.84 | ADAM17 (0.60) | ADAM17MMP2 | |
| SCHEMBL11092735 | 0.82 | MMP2 (0.51) | ADAM17TSHRALDH1A1MMP2MMP9 | |
| SCHEMBL3412312 | 0.82 | ADAM17 (0.44) | ADAM17TSHRMMP2MMP9 | |
| SCHEMBL20134809 | 0.82 | ADAM17 (0.44) | ADAM17CYP2C19TSHRALDH1A1MMP2 | |
| SCHEMBL20135025 | 0.82 | ADAM17 (0.44) | ADAM17CYP2C19TSHRALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252575-B1 | 2-AMINO-2-PHENYLALKANOL DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | OROXCELL (FR) | 2012-12-19 | — | — | EP | disclosed |
| US-8217075-B2 | 2-amino-2-phenyl-alkanol derivatives, their preparation and pharmaceutical compositions containing them | OROXCELL (FR) | 2012-07-10 | — | — | US | disclosed |
| US-8217075-B2 | 2-amino-2-phenyl-alkanol derivatives, their preparation and pharmaceutical compositions containing them | OROXCELL (FR) | 2012-07-10 | — | — | US | disclosed |
| US-8217075-B2 | 2-amino-2-phenyl-alkanol derivatives, their preparation and pharmaceutical compositions containing them | OROXCELL (FR) | 2012-07-10 | — | — | US | disclosed |
| EP-2252575-A1 | 2-AMINO-2-PHENYLALKANOL DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Oroxcell (FR) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009112703-A1 | 2-AMINO-2-PHENYLALKANOL DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | OROXCELL (FR) | 2009-09-17 | — | — | WO | disclosed |
| US-20090197924-A1 | 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | OROXCELL (FR) | 2009-08-06 | — | — | US | disclosed |
| US-20090197924-A1 | 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | OROXCELL (FR) | 2009-08-06 | — | — | US | disclosed |
| US-20090197924-A1 | 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | OROXCELL (FR) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197924-A1 | 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | OPRK1, ALK, AGTR2 | ADAM17 4779/4885CYP2C19 256/4885TSHR 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.