Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MC3R | P41968 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259148 | 1.00 | KDM4E (0.48) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL11259705 | 0.77 | ALDH1A1 (0.49) | KDM4EHCAR2TSHRRAB9AGAA | |
| SCHEMBL11259703 | 0.77 | ALDH1A1 (0.49) | KDM4EHCAR2TSHRRAB9AGAA | |
| SCHEMBL38650644 | 0.77 | ADORA3 (0.57) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL212317 | 0.76 | HTT (0.53) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL4262480 | 0.76 | HTT (0.53) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL2337504 | 0.76 | ALDH1A1 (0.52) | KDM4ENAPRTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8125676 | 0.76 | ALDH1A1 (0.52) | KDM4ENAPRTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2337508 | 0.76 | ALDH1A1 (0.52) | KDM4ENAPRTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6592175 | 0.76 | KDM4E (0.57) | KDM4ENAPRTHCAR2TSHRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051084-A1 | Substituted 1H-1,2,4-triazoles | AMERICAN CYANAMID COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4329463-A | ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4259504-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-31 | — | — | US | disclosed |