Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.60 |
| ▸ | MEN1 | O00255 | 10/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 4/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423785 | 0.88 | KMT2A (0.46) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10021034 | 0.88 | KMT2A (0.46) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL13164871 | 0.75 | MEN1 (1.00) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL17358740 | 0.73 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL13164872 | 0.70 | KMT2A (0.82) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL14039472 | 0.68 | MAPT (0.55) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL12218050 | 0.68 | MEN1 (0.82) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL12218157 | 0.68 | MEN1 (0.82) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL29350119 | 0.68 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL13164870 | 0.68 | MEN1 (0.77) | MAPTMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906354-B2 | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes | BRUKER BIOSPIN CORPORATION (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906354-B2 | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes | BRUKER BIOSPIN CORPORATION (US) | 2014-12-09 | — | — | US | disclosed |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | BRUKER BIOSPIN CORPORATION | 2012-03-08 | — | — | US | disclosed |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | BRUKER BIOSPIN CORPORATION | 2012-03-08 | — | — | US | disclosed |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | QUANTUM MEDICAL HOLDINGS, LLC | 2010-02-11 | — | — | US | disclosed |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | QUANTUM MEDICAL HOLDINGS, LLC | 2010-02-11 | — | — | US | disclosed |
| WO-2010016858-A2 | MOLECULAR IMAGING PROBES | CARESTREAM HEALTH, INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20080181965-A1 | Loaded latex optical molecular imaging probes | QUANTUM MEDICAL HOLDINGS, LLC | 2008-07-31 | — | — | US | disclosed |
| US-20080181965-A1 | Loaded latex optical molecular imaging probes | QUANTUM MEDICAL HOLDINGS, LLC | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181965-A1 | Loaded latex optical molecular imaging probes | MLX, LOXL1, EPX | MAPT 2883/4885MEN1 3048/4885KMT2A 2878/4885 |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | CLTA, COPE, CD68 | MAPT 722/4885MEN1 2615/4885KMT2A 2753/4885 |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | LASP1, LSS, SELL | MAPT 1897/4885MEN1 2790/4885KMT2A 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.