SCHEMBL17358740

SCHEMBL17358740

O=C1NC(=O)N(c2ccccc2)C(=O)C1/C=C/c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.49
ALDH1A1 P00352 7/20 0.49
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
KDM4E B2RXH2 4/20 0.49
L3MBTL1 Q9Y468 4/20 0.49
POLB P06746 4/20 0.49
PKM P14618 3/20 0.49
LMNA P02545 2/20 0.49
MAPK1 P28482 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
NTSR1 P30989 1/20 0.49
ITGA4 P13612 5/20 0.47
ITGB7 P26010 5/20 0.47
HTT P42858 1/20 0.40
PSMD14 O00487 1/20 0.39
MMP2 P08253 1/20 0.39
THRB P10828 1/20 0.39
PPARG P37231 1/20 0.39
NCOA2 Q15596 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112581 0.73 MAPT (0.60) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28305545 0.72 MAPT (0.39) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17408808 0.70 CACNA1B (0.42) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL1639996 0.69 ALDH1A1 (0.42) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL17717930 0.69 ALDH1A1 (0.53) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL13401397 0.68 ALDH1A1 (0.56) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL9980773 0.67 ALDH1A1 (0.57) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL30558271 0.67 MGLL (0.41) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL2364824 0.67 CES2 (0.51) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL13164871 0.66 MEN1 (1.00) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10338290-B2 Cellulose ester film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed