Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | KDR | P35968 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ABL1 | P00519 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.57 |
| ▸ | TUBB | P07437 | 6/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258280 | 0.90 | LMNA (0.49) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| SCHEMBL20657154 | 0.86 | LMNA (0.60) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| Oxfendazole SCHEMBL29351297 | 0.86 | LMNA (0.64) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| Oxfendazole SCHEMBL9818561 | 0.86 | LMNA (0.64) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| Albendazole Oxide SCHEMBL30580728 | 0.84 | LMNA (0.64) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| Albendazole Oxide SCHEMBL17968582 | 0.84 | LMNA (0.64) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| Albendazole Oxide SCHEMBL1649240 | 0.84 | LMNA (0.64) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| SCHEMBL11663912 | 0.81 | LMNA (0.54) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| SCHEMBL11266586 | 0.80 | LMNA (0.53) | LMNACYP1A2HIF1ASMN1; SMN2KDR | |
| SCHEMBL11402164 | 0.80 | TUBB4A (0.76) | LMNACYP1A2HIF1ASMN1; SMN2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321393-A | Method for preparing 2-cyanamidobenzimidazoles or 2-cyanamidobenzoxazoles | SMITHKLINE CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |