Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.60 |
| ▸ | TUBB | P07437 | 5/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Albendazole Oxide SCHEMBL1649240 | 0.91 | LMNA (0.64) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| Albendazole Oxide SCHEMBL17968582 | 0.91 | LMNA (0.64) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| Albendazole Oxide SCHEMBL30580728 | 0.91 | LMNA (0.64) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| SCHEMBL11258288 | 0.86 | LMNA (0.58) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| SCHEMBL11266586 | 0.86 | LMNA (0.53) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| Oxfendazole SCHEMBL9818561 | 0.83 | LMNA (0.64) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| Oxfendazole SCHEMBL29351297 | 0.83 | LMNA (0.64) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| SCHEMBL11663912 | 0.82 | LMNA (0.54) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| Albendazole Oxide SCHEMBL321413 | 0.81 | LMNA (0.55) | LMNACYP1A2HIF1ATUBB4ATUBB | |
| Albendazole Oxide SCHEMBL29564405 | 0.81 | LMNA (0.55) | LMNACYP1A2HIF1ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190016686-A1 | SALTS OF COMPOUNDS HAVING A BENZIMIDAZOLIC STRUCTURE, USES AND PROCESS FOR THE PREPARATION THEREOF | Università degli Studi "G. D'Annunzio" Chieti-Pescara (IT) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016686-A1 | SALTS OF COMPOUNDS HAVING A BENZIMIDAZOLIC STRUCTURE, USES AND PROCESS FOR THE PREPARATION THEREOF | TUBB, TUBB3, TUBB4B | LMNA 3752/4885CYP1A2 688/4885HIF1A 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.