Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.35 |
| ▸ | RARB | P10826 | 5/20 | 0.34 |
| ▸ | RARA | P10276 | 5/20 | 0.34 |
| ▸ | RARG | P13631 | 5/20 | 0.34 |
| ▸ | RXRB | P28702 | 4/20 | 0.34 |
| ▸ | RXRG | P48443 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851470 | 0.79 | RXRA (0.49) | RXRARARBRARARARGRXRB | |
| SCHEMBL17968225 | 0.78 | RXRA (0.49) | RXRARARBRARARARGRXRB | |
| SCHEMBL11214331 | 0.78 | RXRA (0.49) | RXRARARBRARARARGRXRB | |
| SCHEMBL15428156 | 0.77 | PTK2 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13668270 | 0.77 | RXRA (0.36) | RXRARARBRARARARGRXRB | |
| Hydrochloric Acid SCHEMBL17075278 | 0.75 | PTK2 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12418596 | 0.74 | RXRA (0.50) | RXRARARBRARARARGRXRB | |
| SCHEMBL11210750 | 0.74 | ACHE (0.36) | RXRARARBRARARARGMEN1 | |
| SCHEMBL11214828 | 0.73 | MAPT (0.42) | RXRAALDH1A1MEN1BLMKMT2A | |
| SCHEMBL11583537 | 0.72 | ALDH1A1 (0.39) | RXRARARBKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | disclosed |