Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | UBE2B | P63146 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436429 | 0.84 | GSK3B (0.46) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11453442 | 0.81 | ALDH1A1 (0.44) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11258486 | 0.77 | KMT2A (0.47) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8831105 | 0.76 | MAOB (0.54) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL523154 | 0.72 | KMT2A (0.67) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| Alanine SCHEMBL27705533 | 0.71 | ALDH1A1 (0.57) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16398970 | 0.71 | ALOX5 (0.92) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11258457 | 0.70 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL22822228 | 0.70 | MEN1 (0.47) | ALOX5MEN1KMT2AMAPTUBE2B | |
| SCHEMBL8358751 | 0.69 | KMT2A (0.67) | ALOX5MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |