Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200758 | 0.94 | ALDH1A1 (0.62) | KMT2ASLC6A2SLC6A3TDP1RAB9A | |
| SCHEMBL523154 | 0.94 | KMT2A (0.67) | KMT2ASLC6A2SLC6A3TDP1RAB9A | |
| SCHEMBL11116815 | 0.88 | MEN1 (0.72) | KMT2ARAB9AALDH1A1HTTLMNA | |
| SCHEMBL6766307 | 0.87 | HTT (0.65) | KMT2ASLC6A2SLC6A3TDP1RAB9A | |
| SCHEMBL11684706 | 0.87 | ALDH1A1 (0.63) | KMT2ARAB9AALDH1A1HTTALOX5 | |
| SCHEMBL9385816 | 0.86 | ALDH1A1 (0.66) | KMT2ARAB9AALDH1A1HTTMEN1 | |
| SCHEMBL9385826 | 0.86 | ALDH1A1 (0.66) | KMT2ARAB9AALDH1A1HTTMEN1 | |
| SCHEMBL12642453 | 0.86 | KMT2A (0.60) | KMT2ASLC6A2SLC6A3TDP1RAB9A | |
| SCHEMBL10600006 | 0.86 | RAB9A (0.81) | KMT2ATDP1RAB9AALDH1A1HTT | |
| SCHEMBL8141752 | 0.85 | HTT (0.68) | RAB9AALDH1A1HTTNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63132086-A | — | — | None | — | — | JP | disclosed |
| CN-115785154-A | Heteroaromatic ring compounds and medical use thereof | 希格生科（深圳）有限公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2016079759-A1 | NOVEL SINGLE STEP ESTERIFICATION PROCESS OF ALDEHYDES USING A HETEROGENEOUS CATALYST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-05-26 | — | — | WO | disclosed |
| US-8822724-B2 | Method for producing carboxylic acid amide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-09-02 | — | — | US | disclosed |
| EP-2599769-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE | Sumitomo Chemical Company Limited (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-20130123505-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED | 2013-05-16 | — | — | US | disclosed |
| US-5945325-A | MUTANT ENZYME WITH SPECIFIC AMINO ACID SUBSTITUTIONS ISOLATED FROM LIBRARY; FOR DEBLOCKING, DEPROTECTING BETA-LACTAM ANTIBIOTICS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1999-08-31 | — | — | US | disclosed |
| US-5906930-A | NUCLEIC ACID CODING FOR MUTANT ENZYME; FOR REMOVAL OF CARBOXY ACID PROTECTING GROUPS DURING SYNTHESIS OF ANTIBIOTICS LIKE LORACARBEF | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1999-05-25 | — | — | US | disclosed |
| EP-0876490-A1 | PARA-NITROBENZYL ESTERASES WITH ENHANCED ACTIVITY IN AQUEOUS AND NONAQUEOUS MEDIA | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5741691-A | Para-nitrobenzyl esterases with enhanced activity in aqueous and nonaqueous media | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997027304-A9 | PARA-NITROBENZYL ESTERASES WITH ENHANCED ACTIVITY IN AQUEOUS AND NONAQUEOUS MEDIA | — | 1997-10-09 | — | — | WO | disclosed |
| WO-1997027304-A1 | PARA-NITROBENZYL ESTERASES WITH ENHANCED ACTIVITY IN AQUEOUS AND NONAQUEOUS MEDIA | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-07-31 | — | — | WO | disclosed |
| US-4977256-A | Method of eliminating protective groups | LEDERLE (JAPAN), LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| JP-S63132086-A | HEAT-SENSITIVE RECORDING PAPER CONTAINING COMPOUND OF NITROBENZYL BENZOATE AS SENSITIZER | SHIN NISSO KAKO CO LTD | 1988-06-04 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123505-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE | HCAR2, NAAA, FAAH2 | KMT2A 390/4885SLC6A2 3791/4885SLC6A3 3781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.