Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | UBE2B | P63146 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436433 | 0.84 | CES1 (0.45) | RAB9AALDH1A1NPC1SMN1; SMN2CES2 | |
| SCHEMBL11453441 | 0.80 | ALDH1A1 (0.46) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL8831105 | 0.78 | MAOB (0.54) | KMT2AMEN1ALOX5UBE2BRAB9A | |
| SCHEMBL11258477 | 0.77 | ALOX5 (0.51) | KMT2AMEN1ALOX5UBE2BRAB9A | |
| SCHEMBL11258457 | 0.74 | MEN1 (0.65) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL523154 | 0.74 | KMT2A (0.67) | KMT2AMEN1ALOX5RAB9AALDH1A1 | |
| SCHEMBL22822228 | 0.73 | MEN1 (0.47) | KMT2AMEN1ALOX5UBE2BRAB9A | |
| Alanine SCHEMBL27705533 | 0.73 | ALDH1A1 (0.57) | KMT2AMEN1ALOX5UBE2BRAB9A | |
| SCHEMBL8358751 | 0.71 | KMT2A (0.67) | KMT2AMEN1ALOX5RAB9AALDH1A1 | |
| SCHEMBL8813726 | 0.70 | KMT2A (0.53) | KMT2AMEN1ALOX5UBE2BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |