Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.51 |
| ▸ | ATP4B | P51164 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252882 | 0.86 | ATP4A (0.53) | ATP4AATP4BACHECHRNB4CHRNA3 | |
| SCHEMBL11257434 | 0.86 | ATP4A (0.53) | ATP4AATP4BACHECHRNB4CHRNA3 | |
| SCHEMBL11248636 | 0.85 | ADRB2 (0.57) | ACHECHRNB4CHRNA3CHRNA7HDAC3 | |
| SCHEMBL11244652 | 0.78 | CYP2D6 (0.58) | ACHECHRNB4CHRNA3CHRNA7HDAC3 | |
| SCHEMBL9320573 | 0.77 | ATP4A (0.74) | ATP4AATP4BACHECHRNB4CHRNA3 | |
| SCHEMBL5141117 | 0.76 | ATP4A (0.76) | ATP4AATP4BACHECHRNB4CHRNA3 | |
| SCHEMBL9009621 | 0.76 | ATP4A (0.60) | ATP4AATP4BACHECHRNB4CHRNA3 | |
| SCHEMBL11253350 | 0.75 | ADRB2 (0.56) | ACHECHRNB4CHRNA3CHRNA7HDAC3 | |
| SCHEMBL11258032 | 0.74 | HDAC3 (0.52) | ACHECHRNB4CHRNA3CHRNA7HDAC3 | |
| SCHEMBL31063784 | 0.71 | ACHE (0.74) | ATP4AATP4BACHECHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338330-A | HYPOTENSIVE AGENTS | CONTINENTAL PHARMA (BE) | 1982-07-06 | — | — | US | disclosed |