Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244652 | 0.86 | CYP2D6 (0.58) | CYP2D6ACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL11258657 | 0.85 | ATP4A (0.51) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11256396 | 0.84 | ADRB2 (0.51) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11253705 | 0.83 | AMY1A (0.58) | ADRB2ADRB1CYP2D6ADRB3KDM4E | |
| SCHEMBL11249989 | 0.83 | HPSE (0.51) | ADRB2ADRB1CYP2D6ADRB3KDM4E | |
| SCHEMBL11253350 | 0.82 | ADRB2 (0.56) | ADRB2ADRB1CYP2D6ADRB3ACHE | |
| SCHEMBL11252882 | 0.81 | ATP4A (0.53) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11257434 | 0.81 | ATP4A (0.53) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11258032 | 0.81 | HDAC3 (0.52) | ADRB2ADRB1ADRB3ACHEHDAC3 | |
| SCHEMBL11281283 | 0.79 | LMNA (0.53) | ADRB2ADRB1ADRB3ACHEHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338330-A | HYPOTENSIVE AGENTS | CONTINENTAL PHARMA (BE) | 1982-07-06 | — | — | US | claimed |
| US-4338330-A | HYPOTENSIVE AGENTS | CONTINENTAL PHARMA (BE) | 1982-07-06 | — | — | US | disclosed |