Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.60 |
| ▸ | MAOB | P27338 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250033 | 0.82 | MAPT (0.69) | MAOAMAOBMAPTLMNANPC1 | |
| SCHEMBL1115098 | 0.79 | MAPT (0.63) | MAPTLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL30935799 | 0.79 | MAPT (0.63) | MAPTLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL15158561 | 0.78 | MAOA (0.61) | MAOAMAOBMAPTLMNANPC1 | |
| SCHEMBL21082654 | 0.78 | MAPT (0.49) | MAOAMAOBMAPTALDH1A1KMT2A | |
| SCHEMBL5834485 | 0.78 | RAB9A (0.70) | MAPTLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL11249792 | 0.77 | MAPT (0.53) | MAOAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6427216 | 0.77 | KMT2A (0.51) | MAOAMAOBALDH1A1KMT2A | |
| SCHEMBL6836717 | 0.76 | MAPT (0.56) | MAOBMAPTLMNANPC1ALDH1A1 | |
| SCHEMBL11242897 | 0.76 | MAPT (0.53) | MAPTLMNANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351768-A | CARBONLESS, DUPLICATION, INDOLE DYES | STERLING DRUG INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4322352-A | Indolyl phthalide compounds | STERLING DRUG INC. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4307018-A | CHROMOGENS FOR COPYING SYSTEMS | STERLING DRUG INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4251446-A | COLOR PRECURSORS | STERLING DRUG INC. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4189171-A | PRESSURE SENSITIVE, THERMAL AND HECTOGRAPHIC SYSTEMS | STERLING DRUG INC. (US) | 1980-02-19 | — | — | US | disclosed |