Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.34 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264521 | 0.90 | HMOX1 (0.36) | ADRA2CCYP11B1CYP17A1CYP21A2HMOX1 | |
| SCHEMBL11264736 | 0.90 | MAPK1 (0.35) | ADRA2CCYP19A1USP2ALDH1A1LMNA | |
| SCHEMBL11273444 | 0.88 | HMOX1 (0.37) | ADRA2CCYP19A1CYP11B1CYP17A1CYP21A2 | |
| SCHEMBL11269975 | 0.88 | MAPK1 (0.38) | USP2ALDH1A1LMNAALOX15HTT | |
| SCHEMBL11257609 | 0.87 | FNTA (0.39) | ADRA2CCYP19A1CYP11B1CYP17A1CYP21A2 | |
| SCHEMBL11265306 | 0.84 | CYP2A6 (0.45) | CYP19A1CYP11B1HMOX1CYP11B2 | |
| SCHEMBL11260874 | 0.84 | CYP11B1 (0.46) | CYP19A1CYP11B1CYP11B2ALDH1A1LMNA | |
| SCHEMBL11256372 | 0.81 | HMOX1 (0.39) | ADRA2CCYP19A1CYP11B1CYP17A1CYP21A2 | |
| SCHEMBL11261989 | 0.81 | CYP11B1 (0.45) | CYP19A1CYP11B1HMOX1CYP11B2ALDH1A1 | |
| SCHEMBL11261268 | 0.81 | ADRA2C (0.40) | ADRA2CCYP19A1CYP11B1CYP17A1CYP21A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |