Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256513 | 0.95 | ADRA2C (0.39) | ADRA2CCYP19A1CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL11256509 | 0.87 | LMNA (0.38) | ADRA2CCYP19A1MAPTUSP2LMNA | |
| SCHEMBL11264631 | 0.87 | ADRA2C (0.39) | ADRA2CCYP19A1CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL11264094 | 0.85 | ADRA2C (0.38) | ADRA2CCYP19A1USP2LMNAALOX15 | |
| SCHEMBL11270296 | 0.85 | LMNA (0.42) | MAPTUSP2LMNAALOX15MAPK1 | |
| SCHEMBL11254200 | 0.84 | ADRA2C (0.46) | ADRA2CCYP19A1CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL11273444 | 0.83 | HMOX1 (0.37) | ADRA2CCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL11260943 | 0.83 | ADRA2C (0.38) | ADRA2CCYP19A1 | |
| SCHEMBL11263798 | 0.81 | LMNA (0.40) | MAPTUSP2LMNAALOX15MAPK1 | |
| SCHEMBL11258724 | 0.81 | ADRA2C (0.34) | ADRA2CCYP19A1CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |