Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269975 | 0.94 | MAPK1 (0.38) | MAPK1ALOX15USP2LMNAMEN1 | |
| SCHEMBL11260920 | 0.90 | LMNA (0.34) | MAPK1ALOX15USP2LMNAMEN1 | |
| SCHEMBL11258724 | 0.90 | ADRA2C (0.34) | ALOX15USP2LMNACYP19A1ALDH1A1 | |
| SCHEMBL11253462 | 0.89 | MAPK1 (0.37) | MAPK1ALOX15USP2LMNAMEN1 | |
| SCHEMBL11270007 | 0.88 | MAPK1 (0.36) | MAPK1ALOX15USP2LMNAMEN1 | |
| SCHEMBL11252157 | 0.87 | FNTA (0.38) | LMNAKMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL11266076 | 0.85 | TBXAS1 (0.37) | MAPK1ALOX15USP2LMNAMEN1 | |
| SCHEMBL11258901 | 0.84 | CYP2A6 (0.43) | CYP19A1KDM4ETP53TSHR | |
| SCHEMBL11264521 | 0.84 | HMOX1 (0.36) | ADRA2C | |
| SCHEMBL11253398 | 0.83 | ALDH1A1 (0.41) | MAPK1ALOX15LMNACYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |