Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 3/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250351 | 0.90 | HCAR3 (0.49) | HCAR3PLK1THRATHRBEPHX2 | |
| SCHEMBL11260606 | 0.88 | ALDH1A1 (0.50) | HCAR3PLK1THRATHRBL3MBTL1 | |
| SCHEMBL11255414 | 0.85 | HCAR3 (0.62) | HCAR3PLK1THRBALDH1A1HPGD | |
| SCHEMBL15412525 | 0.85 | HCAR3 (0.62) | HCAR3PLK1THRBALDH1A1HPGD | |
| SCHEMBL11262794 | 0.84 | HCAR3 (0.61) | HCAR3PLK1THRBALDH1A1HPGD | |
| SCHEMBL11258316 | 0.83 | HCAR3 (0.49) | HCAR3PLK1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL11559109 | 0.81 | MMP2 (0.56) | MMP2MMP12PLK1THRATHRB | |
| SCHEMBL11252842 | 0.81 | S1PR1 (0.46) | HCAR3PLK1THRATHRBHPGD | |
| SCHEMBL11262791 | 0.81 | HCAR3 (0.50) | HCAR3PLK1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL11258578 | 0.81 | MAPT (0.55) | HCAR3PLK1L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333940-A | Ring-fluorinated 4-(monosubstituted-amino) phenyl compounds in inhibiting atherosclerotic lesion development | AMERICAN CYANAMID COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4243609-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |