Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422915 | 0.83 | THRB (0.39) | THRBLPAR1LPAR3LPAR2LPAR6 | |
| SCHEMBL6180238 | 0.81 | DNM1 (0.56) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL11101061 | 0.81 | DNM1 (0.56) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL4594523 | 0.81 | DNM1 (0.56) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL18240005 | 0.81 | DNM1 (0.56) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL7778179 | 0.81 | DNM1 (0.56) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL9422995 | 0.79 | TSHR (0.42) | THRBLPAR1LPAR3TSHR | |
| SCHEMBL3260445 | 0.78 | DNM1 (0.52) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL3179171 | 0.78 | — | — | |
| SCHEMBL16860496 | 0.78 | ALDH1A1 (0.53) | LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012622-B1 | 1-TOSLOXY-2,2-ETHYLENEDIOXY-6,10-DIMETHYL UNDECANES AND UNDECENES, PROCESS FOR THE PREPARATION OF 2S*,3R*-3-BENZYLOXY-6,6-ETHYLENE DIOXY-2-METHYL-2-(5'-HYDROXY-4'-METHYLPENTYL)-OXEPANE, AND USE OF THE LATTER FOR THE PREPARATION OF OXEPAN-3-OL DERIVATIVES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-12-15 | — | — | EP | disclosed |