Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259010 | 0.79 | DNM1 (0.45) | TSHRTHRBLPAR1LPAR3 | |
| SCHEMBL9423013 | 0.78 | CNR1 (0.43) | LPAR1LPAR3 | |
| SCHEMBL14670792 | 0.78 | LMNA (0.46) | TSHRFAAHTRPV1MAPTHIF1A | |
| SCHEMBL9423104 | 0.78 | PTPN1 (0.39) | MAPT | |
| SCHEMBL9422915 | 0.76 | THRB (0.39) | TSHRTHRBMAPTLPAR1LPAR3 | |
| SCHEMBL9045834 | 0.75 | THRB (0.34) | THRB | |
| SCHEMBL9045458 | 0.75 | THRB (0.34) | THRB | |
| SCHEMBL8798078 | 0.74 | ALDH1A1 (0.53) | TSHRMAPT | |
| SCHEMBL25338044 | 0.72 | TSHR (0.46) | TSHRFAAHTRPV1HIF1A | |
| SCHEMBL4915037 | 0.72 | TSHR (0.46) | TSHRFAAHTRPV1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336436-A | Quick response | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-08-09 | — | — | US | disclosed |