Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731655 | 0.87 | LMNA (0.72) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11268901 | 0.87 | LMNA (0.72) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11266716 | 0.87 | MAPT (0.47) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11272688 | 0.86 | ABCB11 (0.52) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11298608 | 0.85 | ABCB11 (0.77) | ABCB11LMNAMAPTMAPK1GAA | |
| SCHEMBL11268845 | 0.83 | LMNA (0.61) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11203314 | 0.82 | ABCB11 (0.39) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11264433 | 0.82 | LMNA (0.68) | ABCB11LMNAMAPTMAPK1GAA | |
| SCHEMBL11269019 | 0.81 | ABCB11 (0.48) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11299997 | 0.81 | LMNA (0.70) | ABCB11LMNAMAPTMAPK1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |