Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259226 | 0.87 | ABCB11 (0.56) | MAPTLMNAMAPK1ABCB11NAAA | |
| SCHEMBL11274582 | 0.86 | ABCB11 (0.53) | MAPTLMNAMAPK1ABCB11NAAA | |
| SCHEMBL11298734 | 0.84 | ABCB11 (0.59) | MAPTLMNAMAPK1ABCB11HTT | |
| SCHEMBL11205435 | 0.83 | NAAA (0.40) | MAPTLMNAMAPK1NAAAALDH1A1 | |
| SCHEMBL11259163 | 0.83 | MAPT (0.57) | MAPTLMNAMAPK1ABCB11NAAA | |
| SCHEMBL11294281 | 0.81 | LMNA (0.61) | MAPTLMNAMAPK1ABCB11NAAA | |
| SCHEMBL11298608 | 0.77 | ABCB11 (0.77) | MAPTLMNAMAPK1ABCB11 | |
| SCHEMBL11292756 | 0.77 | LMNA (0.52) | MAPTLMNAMAPK1ABCB11ALDH1A1 | |
| SCHEMBL11142160 | 0.76 | LMNA (0.43) | MAPTLMNAMAPK1ABCB11ALDH1A1 | |
| SCHEMBL11205620 | 0.75 | PLAAT3 (0.46) | LMNANAAAALDH1A1TAAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |