Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272688 | 0.95 | ABCB11 (0.52) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11296928 | 0.86 | ABCB11 (0.43) | ABCB11LMNAMAPTMAPK1CYP4F2 | |
| SCHEMBL11264433 | 0.83 | LMNA (0.68) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL11289727 | 0.81 | ABCB11 (0.73) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL15256797 | 0.81 | ABCB11 (0.73) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL11259226 | 0.81 | ABCB11 (0.56) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11208506 | 0.80 | PPARA (0.37) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11206802 | 0.79 | MAPK1 (0.43) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11176469 | 0.79 | LMNA (0.59) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL11268901 | 0.79 | LMNA (0.72) | ABCB11LMNAMAPTMAPK1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |