Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CHAT | P28329 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259417 | 0.89 | CHAT (0.55) | KDM4ECHATALDH1A1MAOBTRPA1 | |
| SCHEMBL11215153 | 0.89 | CHAT (0.55) | KDM4ECHATALDH1A1MAOBTRPA1 | |
| SCHEMBL2502627 | 0.83 | CHAT (0.50) | KDM4ECHATALDH1A1MAOBTRPA1 | |
| SCHEMBL2502624 | 0.83 | CHAT (0.50) | KDM4ECHATALDH1A1MAOBTRPA1 | |
| SCHEMBL7118094 | 0.82 | NFE2L2 (0.58) | KDM4ECHATMAOBTRPA1NFE2L2 | |
| SCHEMBL11544222 | 0.82 | NFE2L2 (0.58) | KDM4ECHATMAOBTRPA1NFE2L2 | |
| SCHEMBL982388 | 0.82 | KMT2A (0.61) | KDM4EALDH1A1CYP2A6MAOBLMNA | |
| SCHEMBL29786760 | 0.82 | KMT2A (0.61) | KDM4EALDH1A1CYP2A6MAOBLMNA | |
| SCHEMBL24385991 | 0.80 | LMNA (0.62) | ALDH1A1CYP2A6MAOBTRPA1NFE2L2 | |
| SCHEMBL192400 | 0.80 | LMNA (0.62) | ALDH1A1CYP2A6MAOBTRPA1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | S.C. JOHNSON & SON, INC. | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | ACHE, DDT, GAP43 | KDM4E 3406/4885CHAT 68/4885ALDH1A1 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.