Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252555 | 0.89 | TRPA1 (0.38) | TRPA1HTTPOLBMAPTALDH1A1 | |
| SCHEMBL11055797 | 0.78 | MAPK1 (0.48) | HTTPOLBALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL11250652 | 0.77 | POLB (0.41) | POLBMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL11721893 | 0.75 | HTT (0.38) | TRPA1HTTPOLBALDH1A1KDM4E | |
| SCHEMBL14868762 | 0.74 | HTR3E (0.41) | POLBMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL11255033 | 0.73 | TSHR (0.42) | POLBMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL11054637 | 0.73 | HTT (0.52) | TRPA1HTTMAPTALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11249260 | 0.72 | HTT (0.38) | HTTPOLBALDH1A1KDM4ELMNA | |
| SCHEMBL11838675 | 0.72 | ALDH1A1 (0.41) | POLBMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL19891465 | 0.71 | LMNA (0.42) | TRPA1POLBMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4025652-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1977-05-24 | — | — | US | disclosed |