Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101149 | 0.76 | PTGS1 (0.49) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL10866556 | 0.74 | PTGS1 (0.43) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11259635 | 0.74 | TLR4 (0.48) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11544353 | 0.74 | PTGS1 (0.50) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL16572623 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL17849498 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL3844494 | 0.74 | TDP1 (0.53) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL3844497 | 0.74 | TDP1 (0.53) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL27463564 | 0.74 | TDP1 (0.53) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL27463562 | 0.74 | TDP1 (0.53) | ALDH1A1TDP1PTGS1MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2087791-A2 | Insecticidal mixture containing gamma-cyhalothrin | Syngenta Limited (GB) | 2009-08-12 | — | — | EP | disclosed |