Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092926 | 0.90 | EBP (0.43) | FFAR1FFAR4LMNAPPARGPPARA | |
| SCHEMBL19127283 | 0.89 | NPC1 (0.38) | CES2CES1HSD17B10CTSL | |
| SCHEMBL11263347 | 0.88 | FFAR1 (0.38) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL11074467 | 0.86 | LMNA (0.46) | FFAR1FFAR4LMNACES2CES1 | |
| SCHEMBL9079230 | 0.82 | KIF11 (0.42) | CES2CES1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11259430 | 0.80 | RXRA (0.38) | FFAR1FFAR4LMNAPPARGPPARD | |
| SCHEMBL9080579 | 0.76 | MAOB (0.43) | MAOBCTSLKMT2A | |
| SCHEMBL20698826 | 0.76 | CCR1 (0.43) | LMNAALDH1A1HPGD | |
| SCHEMBL4874767 | 0.75 | CASP1 (0.44) | LMNACES2CES1ALDH1A1HSD17B10 | |
| SCHEMBL7309094 | 0.75 | CNR1 (0.46) | HSD17B10PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062019-A1 | New phenyl-perhydroazepines | Aktiebolaget Hässle (SE) | 1982-10-06 | — | — | EP | disclosed |