SCHEMBL11259848

SCHEMBL11259848

c1ccc(C2(C3CCCCC3)OCC(CN3CCCCC3)O2)cc1

nearest known ligand 0.80

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.49
TMEM97 Q5BJF2 2/20 0.47
SIGMAR1 Q99720 2/20 0.47
ADRA1D P25100 2/20 0.43
ADRA1A P35348 2/20 0.43
ADRA1B P35368 2/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
SCN1A P35498 1/20 0.43
SCN2A Q99250 1/20 0.43
SCN3A Q9NY46 1/20 0.43
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29449197 0.99 HTR1A (0.48) HTR1ATMEM97SIGMAR1ADRA1DADRA1A
SCHEMBL10807843 0.91 GAA (0.49) HTR1ATMEM97SIGMAR1ADRA1DADRA1A
SCHEMBL27721335 0.81 GRIN1 (0.44) GRIN1GRIN2ACHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL30904664 0.79 HTR1A (0.67) HTR1ATMEM97SIGMAR1ADRA1DADRA1A
Oxapium SCHEMBL24857 0.75 CTDSP1 (0.47) GRIN1GRIN2ACHRM2CHRM4CHRM5
Oxapium SCHEMBL1316687 0.74 CTDSP1 (0.49) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL10807846 0.72 CHRM2 (0.39) HTR1AADRA1AADRA2CGRIN1GRIN2A
SCHEMBL14039627 0.71 CHRM2 (0.43) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL10759760 0.71 TMEM97 (0.49) HTR1ATMEM97SIGMAR1ADRA1DADRA1A
SCHEMBL28130300 0.70 HTR1A (0.47) HTR1ATMEM97SIGMAR1ADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57139075-A None JP disclosed
JP-S57139075-A SEPARATION OF STEREOISOMER OF IODINATED 1-((2-CYCLOHEXYL- 2-PHENYL-1,3-DIOXOLAN-4-YL)METHYL)-1-METHYL-PIPERIDINIUM SANPO KAGAKU KOGYO KK 1982-08-27 JP disclosed