Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721335 | 0.76 | GRIN1 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11259848 | 0.72 | HTR1A (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10807843 | 0.71 | GAA (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL29449197 | 0.71 | HTR1A (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxapium SCHEMBL24857 | 0.70 | CTDSP1 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Oxapium SCHEMBL1316687 | 0.69 | CTDSP1 (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10809023 | 0.67 | CA2 (0.40) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL14039627 | 0.66 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL536771 | 0.65 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL15571396 | 0.63 | ALDH1A1 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097822-B1 | AMINOMETHYLDIOXOLANES AS PARASITICIDES | BAYER AG (DE) | 1987-07-15 | — | — | EP | disclosed |
| EP-0097822-A1 | Aminomethyldioxolanes as parasiticides | BAYER AG (DE) | 1984-01-11 | — | — | EP | disclosed |