Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261726 | 0.91 | LMNA (0.42) | HTTSMN1; SMN2LMNA | |
| SCHEMBL8726366 | 0.81 | PLA2G10 (0.56) | MMP1MMP3MMP9LMNA | |
| SCHEMBL11259867 | 0.78 | ALDH1A1 (0.45) | MMP1MMP3MMP9HTTDAO | |
| SCHEMBL11403843 | 0.78 | FDFT1 (0.40) | HTTMAPT | |
| SCHEMBL11668038 | 0.77 | HTR2A (0.43) | HTTSMN1; SMN2LMNAMAPTDAO | |
| SCHEMBL11266748 | 0.77 | L3MBTL1 (0.42) | MMP1MMP3MMP9SMN1; SMN2 | |
| SCHEMBL11262980 | 0.77 | ALDH1A1 (0.43) | MMP1MMP3MMP9SMN1; SMN2 | |
| SCHEMBL11256499 | 0.76 | NPSR1 (0.49) | MMP1MMP3MMP9LMNA | |
| SCHEMBL11271882 | 0.76 | PLA2G10 (0.53) | MMP1MMP3MMP9 | |
| SCHEMBL11269880 | 0.76 | SIGMAR1 (0.45) | MMP1MMP3MMP9HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005647-B1 | HYDANTOIN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | Lilly Industries Limited (GB) | 1982-06-09 | — | — | EP | disclosed |
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |