Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253421 | 0.90 | ALDH1A1 (0.37) | CYP19A1CYP11B1CYP11B2ALDH1A1MAPK1 | |
| SCHEMBL11260700 | 0.89 | CYP17A1 (0.35) | CYP19A1CYP11B1CYP17A1CYP21A2TSHR | |
| SCHEMBL11264763 | 0.89 | TSHR (0.39) | CYP19A1ALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL11252816 | 0.88 | FNTA (0.38) | CYP19A1CYP11B1CYP17A1CYP21A2ALDH1A1 | |
| SCHEMBL11264053 | 0.85 | CYP11B1 (0.40) | CYP19A1CYP11B1CYP17A1CYP11B2ALOX15 | |
| SCHEMBL11265520 | 0.84 | HMOX1 (0.43) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11273412 | 0.82 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP17A1CYP21A2CYP11B2 | |
| SCHEMBL11257474 | 0.81 | QPCT (0.36) | CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL11265152 | 0.81 | CYP19A1 (0.39) | CYP19A1CYP11B1CYP17A1CYP21A2CYP11B2 | |
| SCHEMBL10782900 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2ALDH1A1TBXAS1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |