Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.40 |
| ▸ | NPC1 | O15118 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255847 | 0.93 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL11255522 | 0.76 | HTR2C (0.39) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL11255763 | 0.76 | HTR2C (0.41) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL11265289 | 0.74 | HTR2C (0.40) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL11256909 | 0.72 | ALDH1A1 (0.39) | RAB9ANPC1LMNAALDH1A1MEN1 | |
| SCHEMBL11253480 | 0.71 | ALDH1A1 (0.41) | RAB9ANPC1LMNAALDH1A1MEN1 | |
| SCHEMBL11270188 | 0.71 | ALDH1A1 (0.41) | RAB9ANPC1LMNAALDH1A1MEN1 | |
| SCHEMBL11258407 | 0.70 | HTR2C (0.43) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL744075 | 0.69 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL11254540 | 0.69 | HTR2C (0.45) | RAB9ANPC1SMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |