Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255763 | 0.79 | HTR2C (0.41) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11256909 | 0.78 | ALDH1A1 (0.39) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11270188 | 0.77 | ALDH1A1 (0.41) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11261226 | 0.76 | RAB9A (0.40) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11253928 | 0.75 | HTR2C (0.40) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11254540 | 0.72 | HTR2C (0.45) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11255635 | 0.67 | HTR2C (0.41) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11264141 | 0.67 | HTR2C (0.43) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11255499 | 0.67 | HDAC6 (0.37) | HTR2CRAD52NPC1RAB9AMAPT | |
| SCHEMBL11270915 | 0.66 | HTR2C (0.40) | HTR2CRAD52NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |