Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.39 |
| ▸ | CBFB | Q13951 | 3/20 | 0.36 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247702 | 0.88 | GPR3 (0.40) | GPR3CBFBRUNX1TRPV1KIF11 | |
| SCHEMBL11262400 | 0.86 | CYP1A2 (0.40) | GPR3CBFBRUNX1TRPV1KIF11 | |
| SCHEMBL11250888 | 0.85 | PIM1 (0.42) | GPR3CBFBRUNX1TRPV1KIF11 | |
| SCHEMBL11246933 | 0.81 | PTGES (0.43) | POLBGAAPTGES | |
| SCHEMBL11250776 | 0.80 | ABCC8 (0.44) | CBFBTRPV1PTGES | |
| SCHEMBL11267114 | 0.79 | TRPV1 (0.45) | TRPV1CYP1A2SCN5ASCN9ASCN2A | |
| SCHEMBL11262992 | 0.77 | AKR1C3 (0.33) | POLBGAAPTGES | |
| SCHEMBL11258445 | 0.77 | ABCC8 (0.36) | POLBGAAPTGES | |
| SCHEMBL11253005 | 0.76 | NOTUM (0.53) | KDM4ENPC1RAB9ALMNACYP3A4 | |
| SCHEMBL11245992 | 0.74 | HDAC3 (0.41) | NPSR1CES1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |