Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273506 | 0.85 | MAPK1 (0.60) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL10062555 | 0.84 | ALDH1A1 (0.47) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11265171 | 0.82 | LMNA (0.54) | LMNAMEN1KMT2AMAPK1ABCB11 | |
| SCHEMBL11269898 | 0.81 | LMNA (0.56) | LMNAMEN1KMT2AMAPK1ABCB11 | |
| SCHEMBL11275748 | 0.80 | LMNA (0.58) | LMNAMEN1KMT2AMAPK1ABCB11 | |
| SCHEMBL11268538 | 0.80 | LMNA (0.58) | LMNAMEN1KMT2AMAPK1ABCB11 | |
| SCHEMBL11266263 | 0.80 | LMNA (0.58) | LMNAMEN1KMT2AMAPK1ABCB11 | |
| SCHEMBL11268263 | 0.80 | LMNA (0.58) | LMNAMEN1KMT2AMAPK1ABCB11 | |
| SCHEMBL30451682 | 0.80 | THRB (0.48) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL10029157 | 0.80 | ALDH1A1 (0.42) | LMNANPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |