Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065008 | 0.82 | NOS1 (0.44) | ALDH1A1HDAC1HDAC6SMN1; SMN2TDP1 | |
| SCHEMBL11260478 | 0.77 | SLC6A4 (0.42) | ALDH1A1MAPTHDAC1HDAC6PTPRB | |
| SCHEMBL11259748 | 0.77 | HDAC1 (0.34) | MAPTHDAC1HDAC6HPGD | |
| SCHEMBL11265409 | 0.75 | HTR6 (0.52) | HTR6HTR2A | |
| SCHEMBL22233466 | 0.71 | CA1 (0.62) | HTR6CA2CA12CA1CA9 | |
| SCHEMBL23299707 | 0.69 | CA1 (0.65) | HTR6CA2ALDH1A1LOXCA12 | |
| SCHEMBL2217200 | 0.68 | HTR6 (0.61) | HTR6CA2ALDH1A1MAPTLOX | |
| SCHEMBL24917161 | 0.67 | HTR6 (0.77) | HTR6CA2ALDH1A1MAPTLOX | |
| SCHEMBL7929144 | 0.67 | HTR6 (0.55) | HTR6CA2CA12CA1CA9 | |
| SCHEMBL7938372 | 0.67 | HTR2A (0.58) | HTR6CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4312869-A | Monosubstituted piperazines | SCIENCE UNION ET CIE (FR) | 1982-01-26 | — | — | US | disclosed |