Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3015461 | 0.87 | TAAR1 (0.50) | HTR6AOC3TAAR1 | |
| SCHEMBL11071906 | 0.84 | AOC3 (0.49) | HTR6AOC3HTR1ADRD2HTR7 | |
| SCHEMBL11063733 | 0.82 | AOC3 (0.47) | HTR6AOC3HTR1ATAAR1 | |
| SCHEMBL11265384 | 0.82 | AOC3 (0.45) | HTR6AOC3TAAR1 | |
| SCHEMBL11064971 | 0.82 | AOC3 (0.53) | HTR6AOC3LMNATAAR1 | |
| SCHEMBL11070162 | 0.81 | SCN4A (0.52) | HTR6AOC3HTR1ALMNATAAR1 | |
| SCHEMBL11064399 | 0.79 | AOC3 (0.51) | HTR6AOC3HTR1AHTR7LMNA | |
| SCHEMBL11071226 | 0.79 | CETP (0.51) | HTR6AOC3MAPK1 | |
| SCHEMBL11064121 | 0.79 | AOC3 (0.51) | HTR6AOC3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL2823992 | 0.79 | HTR6 (0.54) | HTR6HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4312869-A | Monosubstituted piperazines | SCIENCE UNION ET CIE (FR) | 1982-01-26 | — | — | US | claimed |
| US-4312869-A | Monosubstituted piperazines | SCIENCE UNION ET CIE (FR) | 1982-01-26 | — | — | US | disclosed |