Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 3/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263093 | 0.87 | TDO2 (0.41) | TDO2ADORA2AALDH1A1NPSR1MEN1 | |
| SCHEMBL11253084 | 0.86 | ALDH1A1 (0.36) | TDO2ERBB2ADORA2AADORA1ALDH1A1 | |
| SCHEMBL11251011 | 0.86 | BCHE (0.44) | TDO2ERBB2ADORA2AADORA1ALDH1A1 | |
| SCHEMBL11248931 | 0.86 | TDO2 (0.44) | TDO2ERBB2IDO1ALDH1A1CYP1A2 | |
| SCHEMBL11254978 | 0.83 | SYK (0.35) | TDO2ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11254049 | 0.83 | TDO2 (0.37) | TDO2NPSR1 | |
| SCHEMBL11252484 | 0.83 | HSP90AA1 (0.35) | TDO2ALDH1A1TNFCYP11B1CYP11B2 | |
| SCHEMBL11261938 | 0.83 | ALDH1A1 (0.43) | ADORA2AADORA1ALDH1A1NPSR1MEN1 | |
| SCHEMBL11249519 | 0.82 | NPC1 (0.43) | TDO2IDO1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11258335 | 0.82 | ALDH1A1 (0.39) | TDO2IDO1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |