Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271107 | 0.85 | MAPK10 (0.44) | HTR1AHTR7MAPK10PARP1PARP10 | |
| SCHEMBL11255832 | 0.85 | NPC1 (0.40) | NPC1RAB9AHPGDTSHRMAPK10 | |
| SCHEMBL11251733 | 0.82 | ALDH1A1 (0.53) | HTR7MAPK10 | |
| SCHEMBL11259543 | 0.79 | MAPK10 (0.42) | BRD4HTR1AHTR7MAPK10MAPK9 | |
| SCHEMBL28176951 | 0.77 | PARP1 (0.42) | HTR1AHTR7MEN1KMT2AHTR2C | |
| SCHEMBL28542282 | 0.74 | MAPK10 (0.50) | BRD4HTR1AHTR7NPC1RAB9A | |
| SCHEMBL11829588 | 0.74 | MAPK10 (0.40) | BRD4HPGDMAPK10CYP1A2NR1I2 | |
| SCHEMBL1011370 | 0.73 | ALDH1A1 (0.47) | HTR1AHTR7MEN1KMT2AHTR2C | |
| SCHEMBL11267643 | 0.73 | MAPK10 (0.49) | HTR1AHTR7NPC1RAB9AHPGD | |
| SCHEMBL8487986 | 0.70 | NOS2 (0.52) | TSHRPARP1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |