Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 8/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259543 | 0.86 | MAPK10 (0.42) | MAPK10MAPK14MAPK9HTR1AHTR7 | |
| SCHEMBL163051 | 0.77 | MAPK10 (0.55) | MAPK10CYP2A6MAPK14MAPK9 | |
| SCHEMBL29384557 | 0.77 | MAPK10 (0.55) | MAPK10CYP2A6MAPK14MAPK9 | |
| Hydrochloric Acid SCHEMBL27495714 | 0.75 | MAPK10 (0.54) | MAPK10MAPK14MAPK9 | |
| SCHEMBL29010816 | 0.74 | MAPK10 (0.38) | MAPK10BCHEADRA1AOPRK1PDE4D | |
| SCHEMBL30167242 | 0.74 | CYP19A1 (0.41) | MAPK10BCHEHTR2CADRA1AMAPK14 | |
| SCHEMBL1010129 | 0.74 | CYP19A1 (0.41) | MAPK10BCHEHTR2CADRA1AMAPK14 | |
| SCHEMBL11261829 | 0.73 | BRD4 (0.45) | MAPK10PTGS2NR1I2ADORA3HTR2C | |
| SCHEMBL14246803 | 0.73 | ALDH1A1 (0.40) | BCHEHTR1AHTR7NPC1RAB9A | |
| SCHEMBL8215360 | 0.72 | MAPK10 (0.62) | MAPK10PTGS2NR1I2ADORA3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |