Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29526853 | 1.00 | TRPV4 (0.44) | TRPV4CYP19A1HSP90AA1LOXL2LOX | |
| SCHEMBL18661266 | 0.83 | SMN1; SMN2 (0.37) | TRPV4CYP19A1LOXL2LOXTSHR | |
| SCHEMBL28088002 | 0.82 | TSHR (0.35) | TRPV4CYP19A1HSP90AA1LOXL2LOX | |
| SCHEMBL28221312 | 0.82 | RAB9A (0.34) | TRPV4CYP19A1TSHRALOX15CASP1 | |
| SCHEMBL28687790 | 0.81 | CYP19A1 (0.33) | TRPV4CYP19A1HSP90AA1LOXL2LOX | |
| SCHEMBL9589700 | 0.80 | CYP19A1 (0.40) | TRPV4CYP19A1HSP90AA1TSHRALOX15 | |
| SCHEMBL20774860 | 0.80 | CYP19A1 (0.40) | TRPV4CYP19A1HSP90AA1TSHRALOX15 | |
| Ethoxycarbonyl Group SCHEMBL27906093 | 0.77 | KMT2A (0.34) | TRPV4CYP19A1KDM4ENPC1RAB9A | |
| SCHEMBL5720338 | 0.76 | CYP19A1 (0.44) | CYP19A1HSP90AA1TSHRKDM4ENAPRT | |
| SCHEMBL22970752 | 0.75 | ALOX15 (0.41) | TSHRALOX15CASP1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068347-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-04-03 | — | — | WO | claimed |
| EP-3966210-A1 | NOVEL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2022-03-16 | — | — | EP | claimed |
| WO-2021118485-A1 | A PRODUCTION METHOD OF BIOACTIVE SUBSTANCE THYMOKINONE BY USING AY-YLDIZ CATALYST WHITH USE POTENTIAL IN CANCER TREATMENT | CUKUROVA UNIVERSITESI REKTORLUGU (TR) | 2021-06-17 | — | — | WO | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| CN-105358550-B | Histone deacetylase inhibitors | 卡鲁斯治疗有限公司 | 2018-04-06 | — | — | CN | claimed |
| CN-107001389-A | Triazolopyrazine radical derivative as soluble guanylate cyclase activators | 默沙东公司 | 2017-08-01 | — | — | CN | claimed |
| CN-106928247-A | Spiral shell oxindole compounds and its purposes as therapeutic agent | 泽农医药公司 | 2017-07-07 | — | — | CN | claimed |
| CN-106715423-A | Amino-substituted isoxazoles | 拜耳制药股份公司 | 2017-05-24 | — | — | CN | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| CN-104447649-B | Methyl naphtho-[1,2-b] amide compounds and pharmaceutically acceptable salt and its preparation method and application thereof | 辽宁大学 | 2016-08-17 | — | — | CN | claimed |
| CN-103596937-B | Substituted benzamide derivatives | 霍夫曼-拉罗奇有限公司 | 2016-06-29 | — | — | CN | claimed |
| CN-104447649-A | Methylnaphtho-[1,2-b] furan amide compound, and pharmaceutical acceptable salt, preparation method and application of methylnaphtho-[1,2-b] furan amide compound | UNIV LIAONING | 2015-03-25 | — | — | CN | claimed |
| US-12630533-B2 | Heterocyclic compounds useful as KCNT1 inhibitors | ACTIO BIOSCIENCES, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| EP-4735431-A2 | MK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-12577239-B2 | Sulfilimines or sulfoximines containing fungicidal heterocyclic compounds | PI INDUSTRIES LTD. (IN) | 2026-03-17 | — | — | US | disclosed |
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-0102542-B1 | 1,2,4,6-THIATRIAZIN-1,1-DIOXIDE ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1990-07-04 | — | — | EP | disclosed |
| US-4585472-A | PRE- AND POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0102542-A2 | 1,2,4,6-Thiatriazin-1,1-dioxide ethers, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1984-03-14 | — | — | EP | disclosed |
| US-4081542-A | ANOREXIC AGENTS | MERCK & CO., INC. (US) | 1978-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630533-B2 | Heterocyclic compounds useful as KCNT1 inhibitors | KCNT1, KCNT2, KCNJ2 | TRPV4 360/4885CYP19A1 2531/4885HSP90AA1 3458/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | TRPV4 449/4885CYP19A1 1759/4885HSP90AA1 4250/4885 |
| US-12577239-B2 | Sulfilimines or sulfoximines containing fungicidal heterocyclic compounds | SULT1E1, CBR1, SULT1A1 | TRPV4 4529/4885CYP19A1 1565/4885HSP90AA1 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.