Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 4/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267164 | 0.81 | CA12 (0.35) | GAAPARP1PARP10MAPTALDH1A1 | |
| SCHEMBL11269163 | 0.78 | MAPT (0.35) | GAAPARP1PARP10MAPTALDH1A1 | |
| SCHEMBL11280879 | 0.78 | AHR (0.36) | GAAPARP1PARP10MAPTALDH1A1 | |
| SCHEMBL3717613 | 0.77 | GAA (0.57) | GAAPARP1PARP10MAPTALDH1A1 | |
| SCHEMBL11260147 | 0.75 | PNMT (0.36) | MAPTPNMTCA12CA1CA2 | |
| SCHEMBL7385186 | 0.75 | GAA (0.52) | GAAPARP1PARP10MAPTALDH1A1 | |
| SCHEMBL11274713 | 0.74 | PDE3B (0.41) | PARP1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11266164 | 0.73 | ALOX15 (0.36) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11269742 | 0.73 | PNMT (0.41) | MAPTMEN1KMT2APNMTTDP2 | |
| SCHEMBL4991137 | 0.73 | PARP10 (0.56) | GAAPARP1PARP10S1PR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | claimed |
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |