Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985088 | 0.89 | UTS2R (0.37) | UTS2RCA12CA1CA2MMP1 | |
| SCHEMBL18390896 | 0.82 | ALDH1A1 (0.38) | UTS2RCA12CA1CA2MMP1 | |
| SCHEMBL1065657 | 0.82 | CA12 (0.34) | UTS2RCA12CA1CA2MMP1 | |
| SCHEMBL15559120 | 0.81 | CYP2D6 (0.42) | UTS2R | |
| SCHEMBL25099130 | 0.81 | CNR2 (0.38) | UTS2RCA12CA1CA2MMP1 | |
| SCHEMBL13895348 | 0.81 | CA12 (0.33) | UTS2RCA12CA1CA2MMP1 | |
| SCHEMBL18390895 | 0.79 | ALDH1A1 (0.43) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL9994978 | 0.79 | TAS1R3 (0.31) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL6717845 | 0.79 | TAS1R3 (0.50) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL28866263 | 0.79 | CA2 (0.40) | CA12CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361650-A | BACILLUS, STREPTOMYCES OR ACTINOMYCES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0004466-B1 | DEMETHYL MAYTANSINOIDS AND METHODS FOR PRODUCING THEM | Takeda Chemical Industries, Ltd. (JP) | 1982-01-27 | — | — | EP | disclosed |
| US-4307016-A | FUNGICIDES, PROTOZOACIDES OR ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-22 | — | — | US | disclosed |