Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18390895 | 0.84 | ALDH1A1 (0.43) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL11262354 | 0.81 | UTS2R (0.36) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL14533456 | 0.80 | — | — | |
| SCHEMBL8366815 | 0.80 | TAS1R3 (0.44) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL8367404 | 0.80 | CA12 (0.48) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL18390896 | 0.79 | ALDH1A1 (0.38) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL1065657 | 0.79 | CA12 (0.34) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL25099130 | 0.78 | CNR2 (0.38) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL25729370 | 0.77 | CA2 (0.41) | CA1CA2MMP1MMP2TAS1R3 | |
| SCHEMBL9541597 | 0.73 | PRMT3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514468-B2 | Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2009-04-07 | — | — | US | disclosed |