Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 8/20 | 0.49 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270204 | 0.97 | DRD2 (0.53) | HTR7HTR2ADRD2HTR1AFAAH | |
| SCHEMBL11272267 | 0.86 | HTR2A (0.50) | HTR7HTR2ADRD2HTR1ADRD3 | |
| SCHEMBL11273380 | 0.85 | FAAH (0.56) | HTR7HTR2ADRD2HTR1AFAAH | |
| SCHEMBL11269670 | 0.84 | HTR2A (0.55) | HTR7HTR2ADRD2HTR1AFAAH | |
| SCHEMBL11277272 | 0.84 | HTR2A (0.67) | HTR7HTR2ADRD2HTR1ADRD3 | |
| SCHEMBL11815257 | 0.83 | FAAH (0.59) | HTR7HTR2ADRD2HTR1AFAAH | |
| SCHEMBL11811329 | 0.83 | HTR2A (0.58) | HTR7HTR2ADRD2HTR1AFAAH | |
| SCHEMBL11279021 | 0.82 | S1PR5 (0.55) | HTR7HTR2ADRD2HTR1ADRD3 | |
| SCHEMBL11808685 | 0.82 | HTR2A (0.67) | HTR7HTR2ADRD2HTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL11821341 | 0.82 | HTR2A (0.59) | HTR7HTR2ADRD2HTR1AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |