Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.50 |
| ▸ | DRD2 | P14416 | 5/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273380 | 0.88 | FAAH (0.56) | HTR2ADRD2HTR1AHRH3HTR7 | |
| SCHEMBL11277272 | 0.87 | HTR2A (0.67) | HTR2ADRD2HTR1AHTR7DRD3 | |
| SCHEMBL11262385 | 0.86 | HTR7 (0.51) | HTR2ADRD2HTR1AHRH3HTR7 | |
| SCHEMBL11811329 | 0.85 | HTR2A (0.58) | HTR2ADRD2HTR1AHRH3HTR7 | |
| SCHEMBL11815257 | 0.85 | FAAH (0.59) | HTR2ADRD2HTR1AHRH3HTR7 | |
| SCHEMBL11808685 | 0.84 | HTR2A (0.67) | HTR2ADRD2HTR1AHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL11821341 | 0.84 | HTR2A (0.59) | HTR2ADRD2HTR1AHRH3HTR7 | |
| Hydrochloric Acid SCHEMBL11813181 | 0.84 | FAAH (0.58) | HTR2ADRD2HTR1AHRH3HTR7 | |
| SCHEMBL11813702 | 0.84 | HTR2A (0.50) | HTR2ADRD2HTR1AHRH3HTR7 | |
| SCHEMBL11273977 | 0.84 | HTR1A (0.56) | HTR2ADRD2HTR1AHRH3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |