Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 10/20 | 0.50 |
| ▸ | HTR2A | P28223 | 10/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262385 | 0.97 | HTR7 (0.51) | DRD2HTR7HTR1AHTR2AFAAH | |
| SCHEMBL11272267 | 0.83 | HTR2A (0.50) | DRD2HTR7HTR1AHTR2ADRD3 | |
| SCHEMBL11262308 | 0.82 | SLC6A2 (0.56) | DRD2HTR7HTR1AHTR2ADRD3 | |
| SCHEMBL11273380 | 0.82 | FAAH (0.56) | DRD2HTR7HTR1AHTR2AFAAH | |
| SCHEMBL11269670 | 0.82 | HTR2A (0.55) | DRD2HTR7HTR1AHTR2AFAAH | |
| SCHEMBL11270870 | 0.82 | HTR1A (0.59) | DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11277272 | 0.81 | HTR2A (0.67) | DRD2HTR7HTR1AHTR2ADRD3 | |
| SCHEMBL11280944 | 0.81 | HTR7 (0.60) | DRD2HTR7DRD3 | |
| SCHEMBL11265017 | 0.80 | DRD2 (0.69) | DRD2HTR7HTR1AHTR2AFAAH | |
| SCHEMBL11811329 | 0.80 | HTR2A (0.58) | DRD2HTR7HTR1AHTR2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |